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GPR109A controls neutrophil extracellular traps formation and improve early sepsis by regulating ROS/PAD4/Cit-H3 signal axis

BACKGROUND: Neutrophil extracellular traps (NETs) is the key means for neutrophils to resist bacterial invasion. Sepsis is a systemic inflammatory response syndrome caused by infection. METHODS: In our study, qRT-PCR was used to detect the gene expression in neutrophils, Western blot was used to det...

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Detalles Bibliográficos
Autores principales: Guo, Wenjin, Gong, Qian, Zong, Xiaofeng, Wu, Dianjun, Li, Yuhang, Xiao, Huijie, Song, Jie, Zhang, Sheng, Fu, Shoupeng, Feng, Zhichun, Zhuang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887879/
https://www.ncbi.nlm.nih.gov/pubmed/36721229
http://dx.doi.org/10.1186/s40164-023-00376-4