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A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing

Germline Argonautes direct transcriptome surveillance within perinuclear membraneless organelles called nuage. In C. elegans, a family of Vasa-related Germ Line Helicase (GLH) proteins localize in and promote the formation of nuage. Previous studies have implicated GLH proteins in inherited silencin...

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Detalles Bibliográficos
Autores principales: Dai, Siyuan, Tang, Xiaoyin, Li, Lili, Ishidate, Takao, Ozturk, Ahmet R., Chen, Hao, Dude, Altair L., Yan, Yong-Hong, Dong, Meng-Qiu, Shen, En-Zhi, Mello, Craig C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887883/
https://www.ncbi.nlm.nih.gov/pubmed/36070689
http://dx.doi.org/10.1016/j.celrep.2022.111265