Interleukin-27 Promotes Divergent Effects on HIV-1 Infection in Peripheral Blood Mononuclear Cells through BST-2/Tetherin

Interleukin-27 (IL-27) is able to inhibit HIV-1 replication in peripheral blood mononuclear cells (PBMCs), macrophages, and dendritic cells. Here, we identify that IL-27 can produce opposing effects on HIV-1 replication in PBMCs and that the HIV-1 restriction factor BST-2/Tetherin is involved in bot...

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Detalles Bibliográficos
Autores principales: Temerozo, Jairo R., Ferreira, Pedro L. C., Linhares-Lacerda, Leandra, Vieira, Rhaíssa C., Cister-Alves, Bruno, Gobbo, Livia, Ribeiro-Alves, Marcelo, Menna-Barreto, Rubem F. S., Bou-Habib, Dumith Chequer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888194/
https://www.ncbi.nlm.nih.gov/pubmed/36602368
http://dx.doi.org/10.1128/jvi.01752-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888194/
https://www.ncbi.nlm.nih.gov/pubmed/36602368
http://dx.doi.org/10.1128/jvi.01752-22

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