Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial sepsis by inhibiting neutrophil extracellular traps

INTRODUCTION: Neutrophil extracellular traps (NETs) clear pathogens but may contribute Q8 pathogenically to host inflammatory tissue damage during sepsis. Innovative therapeutic agents targeting NET formation and their potentially harmful collateral effects remain understudied. METHODS: We investiga...

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Detalles Bibliográficos
Autores principales: de Araujo, Claudia V., Denorme, Frederik, Stephens, W. Zac, Li, Qing, Cody, Mark J., Crandell, Jacob L., Petrey, Aaron C., Queisser, Kimberly A., Rustad, John L., Fulcher, James M., Evangelista, Judah L., Kay, Michael S., Schiffman, Joshua D., Campbell, Robert A., Yost, Christian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888311/
https://www.ncbi.nlm.nih.gov/pubmed/36733389
http://dx.doi.org/10.3389/fimmu.2022.1046574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888311/
https://www.ncbi.nlm.nih.gov/pubmed/36733389
http://dx.doi.org/10.3389/fimmu.2022.1046574

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