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Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial sepsis by inhibiting neutrophil extracellular traps
INTRODUCTION: Neutrophil extracellular traps (NETs) clear pathogens but may contribute Q8 pathogenically to host inflammatory tissue damage during sepsis. Innovative therapeutic agents targeting NET formation and their potentially harmful collateral effects remain understudied. METHODS: We investiga...
Autores principales: | de Araujo, Claudia V., Denorme, Frederik, Stephens, W. Zac, Li, Qing, Cody, Mark J., Crandell, Jacob L., Petrey, Aaron C., Queisser, Kimberly A., Rustad, John L., Fulcher, James M., Evangelista, Judah L., Kay, Michael S., Schiffman, Joshua D., Campbell, Robert A., Yost, Christian C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888311/ https://www.ncbi.nlm.nih.gov/pubmed/36733389 http://dx.doi.org/10.3389/fimmu.2022.1046574 |
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