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FAM117B promotes gastric cancer growth and drug resistance by targeting the KEAP1/NRF2 signaling pathway

Gastric cancer often shows malignant growth and insensitivity to chemotherapeutic drugs due to the regulation of complex molecular mechanisms, which results in poor prognosis for patients. However, the relevant molecular mechanisms remain unclear. In this study, we reported that family with sequence...

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Detalles Bibliográficos
Autores principales: Zhou, Yunjiang, Chen, Yaxin, Shi, Yongwei, Wu, Leyin, Tan, Yingying, Li, Tao, Chen, Yigang, Xia, Jiazeng, Hu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888386/
https://www.ncbi.nlm.nih.gov/pubmed/36719368
http://dx.doi.org/10.1172/JCI158705