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Angiopep-2 Modified Exosomes Load Rifampicin with Potential for Treating Central Nervous System Tuberculosis

BACKGROUND: Central nervous system tuberculosis (CNS-TB) is the most devastating form of extrapulmonary tuberculosis. Rifampin (RIF) is a first-line antimicrobial agent with potent bactericidal action. Nonetheless, the blood-brain barrier (BBB) limits the therapeutic effects on CNS-TB. Exosomes, how...

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Detalles Bibliográficos
Autores principales: Li, Han, Ding, Yinan, Huang, Jiayan, Zhao, Yanyan, Chen, Wei, Tang, Qiusha, An, Yanli, Chen, Rong, Hu, Chunmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888470/
https://www.ncbi.nlm.nih.gov/pubmed/36733407
http://dx.doi.org/10.2147/IJN.S395246