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Angiopep-2 Modified Exosomes Load Rifampicin with Potential for Treating Central Nervous System Tuberculosis
BACKGROUND: Central nervous system tuberculosis (CNS-TB) is the most devastating form of extrapulmonary tuberculosis. Rifampin (RIF) is a first-line antimicrobial agent with potent bactericidal action. Nonetheless, the blood-brain barrier (BBB) limits the therapeutic effects on CNS-TB. Exosomes, how...
Autores principales: | Li, Han, Ding, Yinan, Huang, Jiayan, Zhao, Yanyan, Chen, Wei, Tang, Qiusha, An, Yanli, Chen, Rong, Hu, Chunmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888470/ https://www.ncbi.nlm.nih.gov/pubmed/36733407 http://dx.doi.org/10.2147/IJN.S395246 |
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