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The signaling function of IDO1 incites the malignant progression of mouse B16 melanoma

Indoleamine 2,3 dioxygenase 1 (IDO1), a leader tryptophan-degrading enzyme, represents a recognized immune checkpoint molecule. In neoplasia, IDO1 is often highly expressed in dendritic cells infiltrating the tumor and/or in tumor cells themselves, particularly in human melanoma. In dendritic cells,...

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Detalles Bibliográficos
Autores principales: Orecchini, E, Belladonna, ML, Pallotta, MT, Volpi, C, Zizi, L, Panfili, E, Gargaro, M, Fallarino, F, Rossini, S, Suvieri, C, Macchiarulo, A, Bicciato, S, Mondanelli, G, Orabona, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888476/
https://www.ncbi.nlm.nih.gov/pubmed/36733497
http://dx.doi.org/10.1080/2162402X.2023.2170095