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Lappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cells

CONTEXT: Lappaol F (LAF), a natural lignan from Arctium lappa Linné (Asteraceae), inhibits tumor cell growth in vitro and in vivo. The underlying mechanism involves the suppression of the Yes-associated protein. However, the specific role of LAF in cell cycle regulation remains unknown. OBJECTIVE: T...

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Detalles Bibliográficos
Autores principales: Yang, Rui-Yi, Tan, Jia-Yi, Liu, Zhe, Shen, Xiao-Ling, Hu, Ying-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888477/
https://www.ncbi.nlm.nih.gov/pubmed/36708218
http://dx.doi.org/10.1080/13880209.2023.2172048