Carboranyl-1,8-naphthalimide intercalators induce lysosomal membrane permeabilization and ferroptosis in cancer cell lines

The synthesis of carborane-1,8-naphthalimide conjugates and evaluation of their DNA-binding ability and anticancer activity were performed. A series of 4-carboranyl-3-nitro-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, were synthesised via amidation and reductive amination reaction...

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Detalles Bibliográficos
Autores principales: Rykowski, Sebastian, Gurda-Woźna, Dorota, Fedoruk-Wyszomirska, Agnieszka, Orlicka-Płocka, Marta, Kowalczyk, Aleksandra, Stączek, Paweł, Denel-Bobrowska, Marta, Biniek-Antosiak, Katarzyna, Rypniewski, Wojciech, Wyszko, Eliza, Olejniczak, Agnieszka B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888480/
https://www.ncbi.nlm.nih.gov/pubmed/36715272
http://dx.doi.org/10.1080/14756366.2023.2171028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888480/
https://www.ncbi.nlm.nih.gov/pubmed/36715272
http://dx.doi.org/10.1080/14756366.2023.2171028

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