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Therapeutic Targeting of DNA Damage Repair in the Era of Precision Oncology and Immune Checkpoint Inhibitors

Cancer manifestation is a multistep process involving accumulation of various genetic and epigenetic changes that results in oncogenic “hallmarks of cancer” processes including genomic instability. Exploitation of aberrant DNA-damage response (DDR) mechanisms in cancer is in part a goal of many ther...

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Detalles Bibliográficos
Autores principales: Clark, Curtis A., Yang, Eddy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Innovative Healthcare Institute 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888518/
https://www.ncbi.nlm.nih.gov/pubmed/36751656
http://dx.doi.org/10.36401/JIPO-22-15