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Therapeutic Targeting of DNA Damage Repair in the Era of Precision Oncology and Immune Checkpoint Inhibitors
Cancer manifestation is a multistep process involving accumulation of various genetic and epigenetic changes that results in oncogenic “hallmarks of cancer” processes including genomic instability. Exploitation of aberrant DNA-damage response (DDR) mechanisms in cancer is in part a goal of many ther...
Autores principales: | Clark, Curtis A., Yang, Eddy S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Innovative Healthcare Institute
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888518/ https://www.ncbi.nlm.nih.gov/pubmed/36751656 http://dx.doi.org/10.36401/JIPO-22-15 |
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