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Ethics of age de-escalation in pediatric vaccine trials: Attending to the case of COVID-19
In the development of new vaccines, many trials use age de-escalation: after establishing safety and efficacy in adult populations, progressively younger cohorts are enrolled and studied. Age de-escalation promotes many values. The responsibility to protect children from potential risks of experimen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888531/ https://www.ncbi.nlm.nih.gov/pubmed/36732168 http://dx.doi.org/10.1016/j.vaccine.2023.01.055 |