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Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver

Nutrient availability fluctuates in most natural populations, forcing organisms to undergo periods of fasting and re-feeding. It is unknown how dietary changes influence liver homeostasis. Here, we show that a switch from ad libitum feeding to intermittent fasting (IF) promotes rapid hepatocyte prol...

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Detalles Bibliográficos
Autores principales: Sarkar, Abby, Jin, Yinhua, DeFelice, Brian C, Logan, Catriona Y, Yang, Yan, Anbarchian, Teni, Wu, Peng, Morri, Maurizio, Neff, Norma F, Nguyen, Huy, Rulifson, Eric, Fish, Matthew, Kaye, Avi Gurion, Martínez Jaimes, Azalia M, Nusse, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889086/
https://www.ncbi.nlm.nih.gov/pubmed/36719070
http://dx.doi.org/10.7554/eLife.82311