A CRISPR screen in intestinal epithelial cells identifies novel factors for polarity and apical transport

Epithelial polarization and polarized cargo transport are highly coordinated and interdependent processes. In our search for novel regulators of epithelial polarization and protein secretion, we used a genome-wide CRISPR/Cas9 screen and combined it with an assay based on fluorescence-activated cell...

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Detalles Bibliográficos
Autores principales: Klee, Katharina MC, Hess, Michael W, Lohmüller, Michael, Herzog, Sebastian, Pfaller, Kristian, Müller, Thomas, Vogel, Georg F, Huber, Lukas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889089/
https://www.ncbi.nlm.nih.gov/pubmed/36661306
http://dx.doi.org/10.7554/eLife.80135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889089/
https://www.ncbi.nlm.nih.gov/pubmed/36661306
http://dx.doi.org/10.7554/eLife.80135

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