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KM-408, a novel phenoxyalkyl derivative as a potential anticonvulsant and analgesic compound for the treatment of neuropathic pain

BACKGROUND: Epilepsy frequently coexists with neuropathic pain. Our approach is based on the search for active compounds with multitarget profiles beneficial in terms of potential side effects and on the implementation of screening for potential multidirectional central activity. METHODS: Compounds...

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Detalles Bibliográficos
Autores principales: Waszkielewicz, Anna, Marona, Henryk, Pańczyk-Straszak, Katarzyna, Filipek, Barbara, Rapacz, Anna, Sałat, Kinga, Kubacka, Monika, Cios, Agnieszka, Fedak, Filip, Walczak, Maria, Hubicka, Urszula, Kwiecień, Anna, Żuromska-Witek, Barbara, Szafrański, Przemysław W., Koczurkiewicz-Adamczyk, Paulina, Pękala, Elżbieta, Przejczowska-Pomierny, Katarzyna, Pociecha, Krzysztof, Wyska, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889419/
https://www.ncbi.nlm.nih.gov/pubmed/36401763
http://dx.doi.org/10.1007/s43440-022-00431-7