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HADHA alleviates hepatic steatosis and oxidative stress in NAFLD via inactivation of the MKK3/MAPK pathway

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a liver metabolic syndrome and still lacks effective treatments because the molecular mechanism underlying the development of NAFLD is not completely understood. We investigated the role of Hydroxyl CoA dehydrogenase alpha subunit (HADHA) in th...

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Detalles Bibliográficos
Autores principales: Ding, Jiexia, Wu, Lili, Zhu, Guoxian, Zhu, Jing, Luo, Pingping, Li, Youming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889437/
https://www.ncbi.nlm.nih.gov/pubmed/36376538
http://dx.doi.org/10.1007/s11033-022-07965-2