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Evaluation of the 5-HT(2C) receptor drugs RO 60-0175, WAY 161503 and mirtazepine in a preclinical model of comorbidity of depression and cocaine addiction

BACKGROUND: Epidemiological data indicate a high rate of comorbidity of depression and cocaine use disorder (CUD). The role of serotonin 2C (5-HT(2C)) receptors in the mechanisms responsible for the coexistence of depression and CUD was not investigated. METHODS: We combined bilateral olfactory bulb...

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Detalles Bibliográficos
Autores principales: Jastrzębska, Joanna, Frankowska, Małgorzata, Smaga, Irena, Hubalewska-Mazgaj, Magdalena, Suder, Agata, Pieniążek, Renata, Przegaliński, Edmund, Filip, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889480/
https://www.ncbi.nlm.nih.gov/pubmed/36374478
http://dx.doi.org/10.1007/s43440-022-00428-2