Extracellular adenosine 5ʹ-diphosphate promotes MCP-1/CCL2 expression via the P2Y(13) purinergic receptor/ERK signaling axis in temporomandibular joint-derived mouse fibroblast-like synoviocytes

BACKGROUND: Temporomandibular joint osteoarthritis (TMJ-OA) causes cartilage degeneration, bone cavitation, and fibrosis of the TMJ. However, the mechanisms underlying the fibroblast-like synoviocyte (FLS)-mediated inflammatory activity in TMJ-OA remain unclear. METHODS AND RESULTS: Reverse transcri...

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Detalles Bibliográficos
Autores principales: Yokota, Seiji, Chosa, Naoyuki, Matsumoto, Shikino, Satoh, Kazuro, Ishisaki, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889505/
https://www.ncbi.nlm.nih.gov/pubmed/36526849
http://dx.doi.org/10.1007/s11033-022-08125-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889505/
https://www.ncbi.nlm.nih.gov/pubmed/36526849
http://dx.doi.org/10.1007/s11033-022-08125-2

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