Suramin prevents the development of diabetic kidney disease by inhibiting NLRP3 inflammasome activation in KK‐Ay mice

AIMS/INTRODUCTION: Nucleotide‐binding oligomerization domain‐like receptor family pyrin domain containing 3 (NLRP3) inflammasomes produce IL‐18 upon being activated by various stimuli via the P2 receptors. Previously, we showed that serum and urine IL‐18 levels are positively associated with albumin...

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Detalles Bibliográficos
Autores principales: Oda, Kaori, Miyamoto, Satoshi, Kodera, Ryo, Wada, Jun, Shikata, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889613/
https://www.ncbi.nlm.nih.gov/pubmed/36308062
http://dx.doi.org/10.1111/jdi.13930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889613/
https://www.ncbi.nlm.nih.gov/pubmed/36308062
http://dx.doi.org/10.1111/jdi.13930

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