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Sensitivity of canine hematological cancers to BH3 mimetics

BACKGROUND: Inhibition of antiapoptotic B‐cell lymphoma 2 (BCL2) proteins by small molecule Bcl‐2 homology 3 (BH3) mimetics causes rapid induction of apoptosis of human hematological cancers in vitro and in vivo. OBJECTIVES: Assess in vitro sensitivity of non‐neoplastic lymphocytes and primary hemat...

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Detalles Bibliográficos
Autores principales: Jegatheeson, Selvi, Cannon, Claire, Mansfield, Caroline, Devlin, Joanne, Roberts, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889650/
https://www.ncbi.nlm.nih.gov/pubmed/36433867
http://dx.doi.org/10.1111/jvim.16587