PSC-derived intestinal organoids with apical-out orientation as a tool to study nutrient uptake, drug absorption and metabolism

Intestinal organoids recapitulate many features of the in vivo gastrointestinal tract and have revolutionized in vitro studies of intestinal function and disease. However, the restricted accessibility of the apical surface of the organoids facing the central lumen (apical-in) limits studies related...

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Detalles Bibliográficos
Autores principales: Kakni, Panagiota, López-Iglesias, Carmen, Truckenmüller, Roman, Habibović, Pamela, Giselbrecht, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889654/
https://www.ncbi.nlm.nih.gov/pubmed/36743212
http://dx.doi.org/10.3389/fmolb.2023.1102209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889654/
https://www.ncbi.nlm.nih.gov/pubmed/36743212
http://dx.doi.org/10.3389/fmolb.2023.1102209

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