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The structure of MadC from Clostridium maddingley reveals new insights into class I lanthipeptide cyclases

The rapid emergence of microbial multi-resistance against antibiotics has led to intense search for alternatives. One of these alternatives are ribosomally synthesized and post-translationally modified peptides (RiPPs), especially lantibiotics. They are active in a low nanomolar range and their high...

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Detalles Bibliográficos
Autores principales: Knospe, C. Vivien, Kamel, Michael, Spitz, Olivia, Hoeppner, Astrid, Galle, Stefanie, Reiners, Jens, Kedrov, Alexej, Smits, Sander H. J., Schmitt, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889658/
https://www.ncbi.nlm.nih.gov/pubmed/36741885
http://dx.doi.org/10.3389/fmicb.2022.1057217