The therapeutic mavericks: Potent immunomodulating chaperones capable of treating human diseases

Two major chaperones, calreticulin (CRT) and binding immunoglobulin protein (GRP78/BiP) dependent on their location, have immunoregulatory or anti‐inflammatory functions respectively. CRT induces pro‐inflammatory cytokines, dendritic cell (DC) maturation and activates cytotoxic T cells against tumou...

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Detalles Bibliográficos
Autores principales: Eggleton, Paul, De Alba, Jorge, Weinreich, Michael, Calias, Perry, Foulkes, Roly, Corrigall, Valerie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889696/
https://www.ncbi.nlm.nih.gov/pubmed/36651415
http://dx.doi.org/10.1111/jcmm.17669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889696/
https://www.ncbi.nlm.nih.gov/pubmed/36651415
http://dx.doi.org/10.1111/jcmm.17669

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