Inhibition of ribosome assembly factor PNO1 by CRISPR/Cas9 technique suppresses lung adenocarcinoma and Notch pathway: Clinical application

Growth is crucially controlled by the functional ribosomes available in cells. To meet the enhanced energy demand, cancer cells re‐wire and increase their ribosome biogenesis. The RNA‐binding protein PNO1, a ribosome assembly factor, plays an essential role in ribosome biogenesis. The purpose of thi...

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Detalles Bibliográficos
Autores principales: Roy, Sanjit K., Srivastava, Shivam, Hancock, Andrew, Shrivastava, Anju, Morvant, Jason, Shankar, Sharmila, Srivastava, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889701/
https://www.ncbi.nlm.nih.gov/pubmed/36625087
http://dx.doi.org/10.1111/jcmm.17657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889701/
https://www.ncbi.nlm.nih.gov/pubmed/36625087
http://dx.doi.org/10.1111/jcmm.17657

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