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Inhibition of ribosome assembly factor PNO1 by CRISPR/Cas9 technique suppresses lung adenocarcinoma and Notch pathway: Clinical application
Growth is crucially controlled by the functional ribosomes available in cells. To meet the enhanced energy demand, cancer cells re‐wire and increase their ribosome biogenesis. The RNA‐binding protein PNO1, a ribosome assembly factor, plays an essential role in ribosome biogenesis. The purpose of thi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889701/ https://www.ncbi.nlm.nih.gov/pubmed/36625087 http://dx.doi.org/10.1111/jcmm.17657 |