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CENPF knockdown inhibits adriamycin chemoresistance in triple-negative breast cancer via the Rb-E2F1 axis

Drug resistance occurs frequently in triple-negative breast cancer (TNBC) and leads to early relapse and short survival. Targeting the DNA damage response (DDR) has become an effective strategy for overcoming TNBC chemoresistance. CENPF (centromere protein) is a key regulator of cell cycle progressi...

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Detalles Bibliográficos
Autores principales: Wang, Depeng, Xu, Wei, Huang, Minghua, Ma, Wei, Liu, Yulu, Zhou, Xingchen, Yang, Qingrui, Mu, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889717/
https://www.ncbi.nlm.nih.gov/pubmed/36720923
http://dx.doi.org/10.1038/s41598-023-28355-z