Cargando…

RNA disruption is a widespread phenomenon associated with stress-induced cell death in tumour cells

We have previously shown that neoadjuvant chemotherapy can induce the degradation of tumour ribosomal RNA (rRNA) in patients with advanced breast cancer, a phenomenon we termed “RNA disruption”. Extensive tumour RNA disruption during chemotherapy was associated with a post-treatment pathological com...

Descripción completa

Detalles Bibliográficos
Autores principales: Butler, Phillipe, Pascheto, Isabella, Lizzi, Michayla, St-Onge, Renée, Lanner, Carita, Guo, Baoqing, Masilamani, Twinkle, Pritzker, Laura B., Kovala, A. Thomas, Parissenti, Amadeo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889758/
https://www.ncbi.nlm.nih.gov/pubmed/36720913
http://dx.doi.org/10.1038/s41598-023-28635-8