Molecular insights into the gating mechanisms of voltage-gated calcium channel Ca(V)2.3

High-voltage-activated R-type Ca(V)2.3 channel plays pivotal roles in many physiological activities and is implicated in epilepsy, convulsions, and other neurodevelopmental impairments. Here, we determine the high-resolution cryo-electron microscopy (cryo-EM) structure of human Ca(V)2.3 in complex w...

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Detalles Bibliográficos
Autores principales: Gao, Yiwei, Xu, Shuai, Cui, Xiaoli, Xu, Hao, Qiu, Yunlong, Wei, Yiqing, Dong, Yanli, Zhu, Boling, Peng, Chao, Liu, Shiqi, Zhang, Xuejun Cai, Sun, Jianyuan, Huang, Zhuo, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889812/
https://www.ncbi.nlm.nih.gov/pubmed/36720859
http://dx.doi.org/10.1038/s41467-023-36260-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889812/
https://www.ncbi.nlm.nih.gov/pubmed/36720859
http://dx.doi.org/10.1038/s41467-023-36260-2

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