The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth

The metalloprotease ADAM17 is a sheddase of key molecules, including TNF and epidermal growth factor receptor ligands. ADAM17 exists within an assemblage, the “sheddase complex,” containing a rhomboid pseudoprotease (iRhom1 or iRhom2). iRhoms control multiple aspects of ADAM17 biology. The FERM doma...

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Detalles Bibliográficos
Autores principales: Badenes, Marina, Burbridge, Emma, Oikonomidi, Ioanna, Amin, Abdulbasit, de Carvalho, Érika, Kosack, Lindsay, Mariano, Camila, Domingos, Pedro, Faísca, Pedro, Adrain, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889915/
https://www.ncbi.nlm.nih.gov/pubmed/36720499
http://dx.doi.org/10.26508/lsa.202201644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889915/
https://www.ncbi.nlm.nih.gov/pubmed/36720499
http://dx.doi.org/10.26508/lsa.202201644

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