Dual targeting of mTOR/IL-17A and autophagy by fisetin alleviates psoriasis-like skin inflammation

Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal hyperplasia and aberrant immune response. In addition to aberrant cytokine production, psoriasis is associated with activation of the Akt/mTOR pathway. mTOR/S6K1 regulates T-lymphocyte activation and migration, k...

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Detalles Bibliográficos
Autores principales: Roy, Tithi, Banang-Mbeumi, Sergette, Boateng, Samuel T., Ruiz, Emmanuelle M., Chamcheu, Roxane-Cherille N., Kang, Lin, King, Judy A., Walker, Anthony L., Nagalo, Bolni Marius, Kousoulas, Konstantin G., Esnault, Stephane, Huang, Shile, Chamcheu, Jean Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889994/
https://www.ncbi.nlm.nih.gov/pubmed/36741386
http://dx.doi.org/10.3389/fimmu.2022.1075804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9889994/
https://www.ncbi.nlm.nih.gov/pubmed/36741386
http://dx.doi.org/10.3389/fimmu.2022.1075804

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