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Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic stem cell tranplantation is predictive of subsequent relapse and survival

Allogeneic stem cell transplantation is used widely in the treatment of hematopoietic malignancy. However, relapse of malignant disease is the primary cause of treatment failure and reflects loss of immunological graft-versus-leukemia effect. We studied the transcriptional and phenotypic profile of...

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Detalles Bibliográficos
Autores principales: Verma, Kriti, Croft, Wayne, Pearce, Hayden, Zuo, Jianmin, Stephens, Christine, Nunnick, Jane, Kinsella, Francesca AM, Malladi, Ram, Moss, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890008/
https://www.ncbi.nlm.nih.gov/pubmed/35924575
http://dx.doi.org/10.3324/haematol.2021.280497