Molecular monitoring of T-cell kinetics and migration in severe neurotoxicity after real-world CD19-specific chimeric antigen receptor T cell therapy

CD19-specific chimeric antigen receptor (CD19-CAR) T-cell therapies mediate durable responses in late-stage B-cell malignancies, but can be complicated by a potentially severe immune effector cell-associated neurotoxicity syndrome (ICANS). Despite broad efforts, the precise mechanisms of ICANS are n...

Descripción completa

Detalles Bibliográficos
Autores principales: Berger, Susanna Carolina, Fehse, Boris, Akyüz, Nuray, Geffken, Maria, Wolschke, Christine, Janson, Dietlinde, Gagelmann, Nico, Luther, Marlene, Wichmann, Dominic, Frenzel, Christian, Thayssen, Guenther, Alegiani, Anna, Badbaran, Anita, Zeschke, Silke, Dierlamm, Judith, Kröger, Nicolaus, Ayuk, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Article - Cell Therapy & Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890009/
https://www.ncbi.nlm.nih.gov/pubmed/35950534
http://dx.doi.org/10.3324/haematol.2022.281110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890009/
https://www.ncbi.nlm.nih.gov/pubmed/35950534
http://dx.doi.org/10.3324/haematol.2022.281110

Ejemplares similares