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High transferrin saturation predicts inferior clinical outcomes in patients with myelodysplastic syndromes

Iron overload (IO) reflected by elevated ferritin is associated with increased mortality in myelodysplastic syndromes (MDS), however, ferritin is an imperfect metric. Elevated labile plasma iron correlates with clinical outcomes and transferrin saturation (TSAT) >80%, but is not readily measurabl...

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Detalles Bibliográficos
Autores principales: Teichman, Jennifer, Geddes, Michelle, Zhu, Nancy, Keating, Mary-Margaret, Sabloff, Mitchell, Christou, Grace, Leber, Brian, Khalaf, Dina, St-Hilaire, Eve, Finn, Nicholas, Shamy, April, Yee, Karen W.L., Storring, John M., Nevill, Thomas J., Delage, Robert, Elemary, Mohamed, Banerji, Versha, Houston, Brett, Mozessohn, Lee, Chodirker, Lisa, Zhang, Liying, Siddiqui, Mohammed, Parmentier, Anne, Leitch, Heather A., Buckstein, Rena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890030/
https://www.ncbi.nlm.nih.gov/pubmed/35979720
http://dx.doi.org/10.3324/haematol.2022.280723