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Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR

Severe acute pancreatitis (SAP) is a lethal gastrointestinal disorder, yet no specific and effective treatment is available. Its pathogenesis involves inflammatory cascade, oxidative stress, and autophagy dysfunction. Xanthohumol (Xn) displays various medicinal properties, including anti-inflammatio...

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Detalles Bibliográficos
Autores principales: Huangfu, Yaru, Yu, Xiuxian, Wan, Chengyu, Zhu, Yuda, Wei, Zeliang, Li, Fan, Wang, Yilan, Zhang, Kun, Li, Shiyi, Dong, Yuman, Li, Yangying, Niu, Hai, Xin, Guang, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890064/
https://www.ncbi.nlm.nih.gov/pubmed/36744265
http://dx.doi.org/10.3389/fphar.2023.1105726