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Downregulation of nuclear STAT2 protein in the spinal dorsal horn is involved in neuropathic pain following chronic constriction injury of the rat sciatic nerve

Regulation of gene transcription in the spinal dorsal horn (SDH) plays a critical role in the pathophysiology of neuropathic pain. In this study, we investigated whether the transcription factor STAT2 affects neuropathic pain and evaluated its possible mechanisms. A proteomic analysis showed that th...

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Detalles Bibliográficos
Autores principales: Huang, Zhifeng, Ding, Zijing, Xu, Yangting, Xi, Caiyun, He, Liqiong, Luo, Hui, Guo, Qulian, Huang, Changsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890072/
https://www.ncbi.nlm.nih.gov/pubmed/36744245
http://dx.doi.org/10.3389/fphar.2023.1069331