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TWEAK–Fn14–RelB Signaling Cascade Promotes Stem Cell–like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse

Disease recurrence in high-grade serous ovarian cancer may be due to cancer stem–like cells (CSC) that are resistant to chemotherapy and capable of reestablishing heterogeneous tumors. The alternative NF-κB signaling pathway is implicated in this process; however, the mechanism is unknown. Here we s...

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Detalles Bibliográficos
Autores principales: Holmberg, Ryne, Robinson, Mikella, Gilbert, Samuel F., Lujano-Olazaba, Omar, Waters, Jennifer A., Kogan, Emily, Velasquez, Candyd Lace R., Stevenson, Denay, Cruz, Luisjesus S., Alexander, Logan J., Lara, Jacqueline, Mu, Emily M., Camillo, Jared Rafael, Bitler, Benjamin G., Huxford, Tom, House, Carrie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890141/
https://www.ncbi.nlm.nih.gov/pubmed/36214671
http://dx.doi.org/10.1158/1541-7786.MCR-22-0486