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TWEAK–Fn14–RelB Signaling Cascade Promotes Stem Cell–like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse
Disease recurrence in high-grade serous ovarian cancer may be due to cancer stem–like cells (CSC) that are resistant to chemotherapy and capable of reestablishing heterogeneous tumors. The alternative NF-κB signaling pathway is implicated in this process; however, the mechanism is unknown. Here we s...
Autores principales: | Holmberg, Ryne, Robinson, Mikella, Gilbert, Samuel F., Lujano-Olazaba, Omar, Waters, Jennifer A., Kogan, Emily, Velasquez, Candyd Lace R., Stevenson, Denay, Cruz, Luisjesus S., Alexander, Logan J., Lara, Jacqueline, Mu, Emily M., Camillo, Jared Rafael, Bitler, Benjamin G., Huxford, Tom, House, Carrie D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890141/ https://www.ncbi.nlm.nih.gov/pubmed/36214671 http://dx.doi.org/10.1158/1541-7786.MCR-22-0486 |
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