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Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn’s Disease

BACKGROUND: Crohn’s disease is a lifelong disease characterized by chronic inflammation of the gastrointestinal tract. Defining the cellular and transcriptional composition of the mucosa at different stages of disease progression is needed for personalized therapy in Crohn’s. METHODS: Ileal biopsies...

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Detalles Bibliográficos
Autores principales: Maddipatla, Sushma Chowdary, Kolachala, Vasantha L, Venkateswaran, Suresh, Dodd, Anne F, Pelia, Ranjit Singh, Geem, Duke, Yin, Hong, Sun, Yutong, Xu, Congmin, Mo, Angela, Kosters, Astrid, Yang, Junkai, Matthews, Jason D, Ghosn, Eliver, Kugathasan, Subra, Qiu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890215/
https://www.ncbi.nlm.nih.gov/pubmed/36206201
http://dx.doi.org/10.1093/ibd/izac201