Structural and biochemical basis of interdependent FANCI‐FANCD2 ubiquitination

Di‐monoubiquitination of the FANCI‐FANCD2 (ID2) complex is a central and crucial step for the repair of DNA interstrand crosslinks via the Fanconi anaemia pathway. While FANCD2 ubiquitination precedes FANCI ubiquitination, FANCD2 is also deubiquitinated at a faster rate than FANCI, which can result...

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Detalles Bibliográficos
Autores principales: Lemonidis, Kimon, Rennie, Martin L, Arkinson, Connor, Chaugule, Viduth K, Clarke, Mairi, Streetley, James, Walden, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890228/
https://www.ncbi.nlm.nih.gov/pubmed/36385258
http://dx.doi.org/10.15252/embj.2022111898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890228/
https://www.ncbi.nlm.nih.gov/pubmed/36385258
http://dx.doi.org/10.15252/embj.2022111898

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