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New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs

and polyfluoroalkyl substances (PFASs) have been associated with increased blood lipids in humans. Perfluorooctanoic acid (PFOA) has been also linked with elevated alanine transferase (ALT) serum levels in humans, and in rodents the liver is a main target organ for many PFASs. With the focus on New...

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Detalles Bibliográficos
Autores principales: Fragki, Styliani, Louisse, Jochem, Bokkers, Bas, Luijten, Mirjam, Peijnenburg, Ad, Rijkers, Deborah, Piersma, Aldert H., Zeilmaker, Marco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890272/
https://www.ncbi.nlm.nih.gov/pubmed/36535450
http://dx.doi.org/10.1016/j.fct.2022.113559