Binding Modes of a Cytotoxic Dinuclear Copper(II) Complex with Phosphate Ligands Probed by Vibrational Photodissociation Ion Spectroscopy

[Image: see text] The dinuclear copper complex bearing a 2,7-disubstituted-1,8-naphthalenediol ligand, [(HtomMe){Cu(OAc)}(2)](OAc), a potential anticancer drug able to bind to two neighboring phosphates in the DNA backbone, is endowed with stronger cytotoxic effects and inhibition ability of DNA syn...

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Detalles Bibliográficos
Autores principales: Giampà, Marco, Corinti, Davide, Maccelli, Alessandro, Fornarini, Simonetta, Berden, Giel, Oomens, Jos, Schwarzbich, Sabrina, Glaser, Thorsten, Crestoni, Maria Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890465/
https://www.ncbi.nlm.nih.gov/pubmed/36655890
http://dx.doi.org/10.1021/acs.inorgchem.2c02091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890465/
https://www.ncbi.nlm.nih.gov/pubmed/36655890
http://dx.doi.org/10.1021/acs.inorgchem.2c02091

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