Lack of SIRP‐alpha reduces lung cancer growth in mice by promoting anti‐tumour ability of macrophages and neutrophils

OBJECTIVES: Signal regulatory protein‐alpha (SIRPα) is a transmembrane glycoprotein specifically expressed on myeloid cells. Blockade of SIRPα/CD47 interaction is effective in combinational therapy of some cancers. This study aimed to explore into the role and underlying molecular mechanisms of SIRP...

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Detalles Bibliográficos
Autores principales: Pan, Linyue, Wang, Bin, Chen, Mengjie, Ma, Yuan, Cui, Bo, Chen, Zhihong, Song, Yuanlin, Hu, Lijuan, Jiang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890530/
https://www.ncbi.nlm.nih.gov/pubmed/36419386
http://dx.doi.org/10.1111/cpr.13361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890530/
https://www.ncbi.nlm.nih.gov/pubmed/36419386
http://dx.doi.org/10.1111/cpr.13361

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