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Structure-based approach: molecular insight of pyranocumarins against α-glucosidase through computational studies

α-glucosidase is an enzyme that catalyzes the release of α-glucose molecules through hydrolysis reactions. Regulation of this enzyme can increase sugar levels in type-2 diabetes mellitus (DM) patients. Pyranocoumarin derivatives have been identified as α-glucosidase inhibitors. Through an in silico...

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Detalles Bibliográficos
Autores principales: Abdjan, Muhammad Ikhlas, Aminah, Nanik Siti, Kristanti, Alfinda Novi, Siswanto, Imam, Ilham, Baso, Wardana, Andika Pramudya, Takaya, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890569/
https://www.ncbi.nlm.nih.gov/pubmed/36756595
http://dx.doi.org/10.1039/d2ra07537g