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Sunitinib efficacy with minimal toxicity in patient-derived retinoblastoma organoids
BACKGROUND: Recurrence of retinoblastoma (RB) following chemoreduction is common and is often managed with local (intra-arterial/intravitreal) chemotherapy. However, some tumors are resistant to even local administration of maximum feasible drug dosages, or effective tumor control and globe preserva...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890748/ https://www.ncbi.nlm.nih.gov/pubmed/36726110 http://dx.doi.org/10.1186/s13046-023-02608-1 |