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Sunitinib efficacy with minimal toxicity in patient-derived retinoblastoma organoids

BACKGROUND: Recurrence of retinoblastoma (RB) following chemoreduction is common and is often managed with local (intra-arterial/intravitreal) chemotherapy. However, some tumors are resistant to even local administration of maximum feasible drug dosages, or effective tumor control and globe preserva...

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Detalles Bibliográficos
Autores principales:	Srimongkol, Atthapol, Laosillapacharoen, Natanan, Saengwimol, Duangporn, Chaitankar, Vijender, Rojanaporn, Duangnate, Thanomchard, Thanastha, Borwornpinyo, Suparerk, Hongeng, Suradej, Kaewkhaw, Rossukon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890748/ https://www.ncbi.nlm.nih.gov/pubmed/36726110 http://dx.doi.org/10.1186/s13046-023-02608-1

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