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Exosomal HSP90 induced by remote ischemic preconditioning alleviates myocardial ischemia/reperfusion injury by inhibiting complement activation and inflammation

BACKGROUND/AIMS: The activation of the complement system and subsequent inflammatory responses are important features of myocardial ischemia/reperfusion (I/R) injury. Exosomes are nanoscale extracellular vesicles that play a significant role in remote ischemic preconditioning (RIPC) cardioprotection...

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Detalles Bibliográficos
Autores principales: Cheng, Xiao-Fang, He, Shi-Tao, Zhong, Guo-Qiang, Meng, Jian-Jun, Wang, Min, Bi, Qi, Tu, Rong-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890892/
https://www.ncbi.nlm.nih.gov/pubmed/36726083
http://dx.doi.org/10.1186/s12872-023-03043-y