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Thiourea fused γ-amino alcohol organocatalysts for asymmetric Mannich reaction of β-keto active methylene compounds with imines

Catalytic functionality of new optically active thiourea fused γ-amino alcohols was examined in the asymmetric Mannich reaction of β-keto active methylene compounds with imines to afford chiral Mannich products, β-amino keto compounds, with continuous chiral centers, that are versatile synthetic int...

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Detalles Bibliográficos
Autores principales: Nomura, Miku, Begum, Zubeda, Seki, Chigusa, Okuyama, Yuko, Kwon, Eunsang, Uwai, Koji, Tokiwa, Michio, Tokiwa, Suguru, Takeshita, Mitsuhiro, Nakano, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891089/
https://www.ncbi.nlm.nih.gov/pubmed/36756606
http://dx.doi.org/10.1039/d2ra08317e