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Accurate estimation of molecular counts from amplicon sequence data with unique molecular identifiers
MOTIVATION: Amplicon sequencing is widely applied to explore heterogeneity and rare variants in genetic populations. Resolving true biological variants and quantifying their abundance is crucial for downstream analyses, but measured abundances are distorted by stochasticity and bias in amplification...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891248/ https://www.ncbi.nlm.nih.gov/pubmed/36610988 http://dx.doi.org/10.1093/bioinformatics/btad002 |